Health Monitoring in Accordance with FELASA Recommendations

Date of issue:19 January 2018
Species:mice (exclusively)
Housing:SPF, Barrier IVC/1.

Test FrequencyLatest Test DateNumberLatest resultTesting Laborat.Test MethodHistorical result (<18 months)
MHV (Mouse hepatitis virus)3 months21 Sept 20170/5negative1IFA0/64
EDIM (mouse ROTA)3 months21 Sept 20170/5negative1IFA0/64
MVM, (NS1*)3 months21 Sept 20170/5negative1PCR0/64
MPV 1+2, (NS1*)3 months21 Sept 20170/5negative1PCR0/64
Theiler (TMEV)3 months21 Sept 20170/5negative1IFA0/64
MNV (Mouse norovirus)3 months21 Sept 20170/5negative1IFA0/64
PVMAnnually09 Feb 20170/19negative1IFA0/19
SENDAnnually09 Feb 20170/19negative1IFA0/19
ECTRO (Ectromelia virus)Annually09 Feb 20170/19negative1IFA0/19
LCMV (Lymphocytic choriomeningitis virus)Annually09 Feb 20170/19negative1IFA0/19
MAD (Mouse adenovirus) 1+2Annually09 Feb 20170/19negative1IFA0/19
REO-3 (Reovirus 3)Annually09 Feb 20170/19negative1IFA0/19
Bacteria, Mycoplasma and fungi 
Pasteurella pneumotropica3 months25 Sept 20170/5negative1IFA0/69
Streptococci Beta-haemolytic (not group D)3 months25 Sept 20170/5negative2CULT0/84
Streptococcus pneumoniae3 months25 Sept 20170/5negative2CULT0/64
Helicobacter spp.3 months25 Sept 20170/5negative1PCR0/64
CPIL (Clostridium piliforme)Annually09 Feb 20170/19negative1IFA0/19
Citrobacter rodentiumAnnually15 Feb 20170/19negative2CULT0/19
Corynebacterium kutscheriAnnually15 Feb 20170/19negative2CULT0/19
Mycoplasma pneumoniaeAnnually09 Feb 20170/19negative1IFA0/19
Salmonella spp.Annually15 Feb 20170/19negative2CULT0/19
Streptobacillus moniliformisAnnually15 Feb 20170/19negative2CULT0/19
Ecto parasites 
Mites3 months25 Sept 20170/5negative2MICR0/64
Lices3 months25 Sept 20170/5negative2MICR0/64
Endo parasites 
Aspiculuris tetraptera3 months25 Sept 20170/5negative2MICR0/84
Syphacia muris3 months25 Sept 20170/5negative2MICR0/64
Syphacia obvelata3 months25 Sept 20170/5negative2MICR0/64
Entamoeba muris3 months25 Sept 20170/5negative2MICR7/64
Giardia sp.3 months25 Sept 20170/5negative2MICR0/64
Spironucleus sp.3 months25 Sept 20170/5negative2MICR0/64
Trichomonads3 months25 Sept 20170/5negative2MICR0/64
Non pathogen endoparasites 
Hexamastix sp.3 months25 Sept 20170/5negative2MICR4/64
Chilomastix sp.3 months25 Sept 20170/5negative2MICR0/64
Pathological lesions 
External3 months25 Sept 20170/5negative2PATH/HIST0/64
Necropsy3 months25 Sept 20170/5negative2PATH/HIST0/64


Data are expressed as number positive/number tested


Abbreviation used in this report:


ELISA  = enzyme linked immunosorbent assay, MICR = microscopy, IFA = immunoflorescence assay, CULT = culture, PATH = gross pathology, PCR = polymerase chain reaction, HIST = histopathology, NT = not tested



Diagnostic laboratories:

1/ BioDoc LTD, Feodor Lynen str. 23, 30625 Hannover, Germany

2/ Central Veterinary Institute, Tábornok u. 2, 1149 Budapest, Hungary.




The sentinel program consists of at least quarterly necropsy, serology, and parasitology following the recommendation of FELASA. These sentinels are housed on a sample of dirty bedding from the other animals’ cages from a given room.

* NS1 = NS1 protein is highly conserved among rodent parvoviruses and thus serves as a generic assay for parvovirus seroconversion.


The ‘Serology/Parasitology History’ provided above indicates previous sentinel results and is not a guarantee of the current or future health status; it is only an indicator of the previous health status. A conventional animal house is running in the same building with MHV and pinworms.


This document has been changed conforming the new recommendations made by the FELASA working group on revision of guidelines for health monitoring of rodents and rabbits in February, 2014.







                                                                                                                        Balazs Benyei               


1094. Budapest, Tűzoltó utca 37/47, Hungary

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