Health Monitoring in Accordance with FELASA Recommendations

Date of issue:21 November 2019
Species:mice (exclusively)
Housing:SPF, Barrier IVC/1.

Test FrequencyLatest Test DateNumberLatest resultTesting Laborat.Test MethodHistorical result (<18 months)
MHV (Mouse hepatitis virus)3 months24 May 20190/15negative1IFA0/40
EDIM (mouse ROTA)3 months24 May 20190/15negative1IFA0/40
MVM, (NS1*)3 months24 May 20190/15negative1PCR0/40
MPV 1+2, (NS1*)3 months24 May 20190/15negative1PCR0/40
Theiler (TMEV)3 months24 May 20190/15negative1IFA0/40
MNV (Mouse norovirus)3 months24 May 20190/15negative1IFA0/40
PVMAnnually17 May 20180/10negative1IFA0/10
SENDAnnually17 May 20180/10negative1IFA0/10
ECTRO (Ectromelia virus)Annually17 May 20180/10negative1IFA0/10
LCMV (Lymphocytic choriomeningitis virus)Annually17 May 20180/10negative1IFA0/10
MAD (Mouse adenovirus) 1+2Annually17 May 20180/10negative1IFA0/10
REO-3 (Reovirus 3)Annually17 May 20180/10negative1IFA0/10
Bacteria, Mycoplasma and fungi 
Pasteurella pneumotropica3 months24 May 20190/15negative1IFA0/40
Streptococci Beta-haemolytic (not group D)3 months24 May 20190/15negative2CULT0/50
Streptococcus pneumoniae3 months24 May 20190/15negative2CULT0/50
Helicobacter spp.3 months24 May 20190/15negative1PCR0/40
CPIL (Clostridium piliforme)Annually17 May 20180/10negative1IFA0/10
Citrobacter rodentiumAnnually23 May 20180/10negative2CULT0/10
Corynebacterium kutscheriAnnually23 May 20180/10negative2CULT0/10
Mycoplasma pneumoniaeAnnually17 May 20180/10negative1IFA0/10
Salmonella spp.Annually23 May 20180/10negative2CULT0/10
Streptobacillus moniliformisAnnually17 May 20180/10negative2CULT0/35
Ecto parasites 
Mites3 months24 May 20190/15negative2MICR0/40
Lices3 months24 May 20190/15negative2MICR0/40
Endo parasites 
Aspiculuris tetraptera3 months24 May 20190/15negative2MICR0/40
Syphacia muris3 months24 May 20190/15negative2MICR0/40
Syphacia obvelata3 months24 May 20190/15negative2MICR0/40
Entamoeba muris3 months24 May 20190/15negative2MICR0/40
Giardia sp.3 months24 May 20190/15negative2MICR0/40
Spironucleus sp.3 months24 May 20190/15negative2MICR0/40
Trichomonads3 months24 May 20190/15negative2MICR0/40
Non pathogen endoparasites 
Hexamastix sp.3 months24 May 20190/15negative2MICR0/40
Chilomastix sp.3 months24 May 20190/15negative2MICR0/40
Pathological lesions 
External3 months24 May 20190/15negative2PATH/HIST0/40
Necropsy3 months24 May 20190/15negative2PATH/HIST0/40


Data are expressed as number positive/number tested


Abbreviation used in this report:


ELISA  = enzyme linked immunosorbent assay, MICR = microscopy, IFA = immunoflorescence assay, CULT = culture, PATH = gross pathology, PCR = polymerase chain reaction, HIST = histopathology, NT = not tested



Diagnostic laboratories:

1/ BioDoc LTD, Feodor Lynen str. 23, 30625 Hannover, Germany

2/ Central Veterinary Institute, Tábornok u. 2, 1149 Budapest, Hungary.




The sentinel program consists of at least quarterly necropsy, serology, and parasitology following the recommendation of FELASA. These sentinels are housed on a sample of dirty bedding from the other animals’ cages from a given room.

* NS1 = NS1 protein is highly conserved among rodent parvoviruses and thus serves as a generic assay for parvovirus seroconversion.


The ‘Serology/Parasitology History’ provided above indicates previous sentinel results and is not a guarantee of the current or future health status; it is only an indicator of the previous health status. A conventional animal house is running in the same building with MHV and pinworms.


This document has been changed conforming the new recommendations made by the FELASA working group on revision of guidelines for health monitoring of rodents and rabbits in February, 2014.







                                                                                                                        Balazs Benyei               


1094. Budapest, Tűzoltó utca 37/47, Hungary

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